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Rick Stewart didn't understand about the laburnum trees growing in Bulgaria and their potential to produce a drug for giving up smoking back when he was the president of the pharmaceutical business Amarin. He was too deep inside the drug industry, a place frequently criticized for its short-sighted focus on profits.

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Just then might he find the opportunity in those yellow-flowering trees. Now, with the assistance of the National Institutes of Health, Stewart is trying to present the laburnum-derived drug to the U.S. market. The pill works by interrupting tobacco yearnings, just like Pfizer's top-selling Chantix, but potentially without that drug's high-profile negative effects and at a much lower cost.

Today, scientists are delighted about what might be the very first brand-new treatment for smoking cessation to emerge in years. "We need this," stated David Shurtleff, deputy director of the NIH Center for Complementary and Integrative Health, discussing why his company is assisting to get the drug authorized. But laburnum's promise is not brand-new.

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From left, Ronald Martell, Rick Stewart and Anthony Clarke of Extab. Stewart wishes to rebrand the smoking-cessation drug Tabex as Extab for sale in Western European and U.S. markets. (Tom Pilston) In 2007, Stewart had staked his task as the head of Amarin on a various drug. Miraxion was for treating Huntington's Illness, and early on it revealed indications of enhancing signs of the neurological condition.

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Financiers in Amarin, a $240 million business based in New Jersey, were stunned. The company's stock fell 80 percent. Stewart ran out a job. "The CEO always falls on his sword," Stewart, 56, states now. However Miraxion did appear to help patients with Huntington's it simply took longer than the 6 months allotted throughout the medical trials.

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This led Stewart and Anthony Clarke, who also lost his task after running the trials for Amarin, to wonder what other misconstrued drugs were out there. They went on a hunt. "These drugs are neglected or unwanted. benefits of quitting smoking need tender loving care," Stewart states. "And pharma, for whatever factor, can't be troubled with them." They set up a small company outside London called Ricanto a mash-up of their first names.